LyoConstellation Development & Pilot Freeze Dryers provide the largest process space in their class, allowing development of highly aggressive cycles. Each unit can hold 100mTorr while shelves are at +40⁰C fully loaded. Equipped and controlled as a production system, LyoConstellation offers the same software and technology options as smaller systems for a seamless approach to scale-up while being designed for line integration - including being isolator-ready and suitable for clean room installation.

Available in three shelf sizes: 1m₂, 2m₂ and 3m₂, LyoConstellation lyophilizers are configured to order for faster than average market delivery.

LyoConstellation offers a comprehensive range of options for secure, best manufacturing practices for high-value products, including controlled ice nucleation, fluid condenser cooling and large diameter vapor ports for high flow.

Showcasing SP's Line of Sight technologies, the LyoConstellation is available with ControLyo Technology, Tempris wireless temperature sensors and (SMART) LyoFlux TDLAS mass flow measurement.

Specifications

Chamber	Pressure rated (ASME or PED) for SIP/CIP & ControLyo® Constant load height of 43.5" /1105mm (S20 and S30) Pirani and Capacitance Manometer as standard, 2 additional validation ports
Access Doors	S10 has an auto locking chamber door to the isolator/cleanroom only S20 and S30 have an auto locking, loading slot door to isolator / cleanroom with powered opening and maintenance door access from machine room.
Large Diameter Vapor Port	Cleanable butterfly valve Optional TDLAS spool, pressure rated
Condenser	1:1 shelf to condenser surface area Pressure rated execution (ASME or PED) for SIP/CIP Pirani and Capacitance Manometer as standard, 2 additional validation ports
Controller	LyoS - Windows-based; features include Batch Reports, 21 CFR Part 11 compliance capabilities (SEC3) and Uninterruptible Power Supply (UPS)
Cleaning Options	Full Steam in Place (SIP) & Clean in Place (CIP) execution with manual / H2O2 option (S10)
Validation Options	Full validation documentation package and support available

Contact

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Sysmex Nederland B.V.

Ecustraat 11

4879 NP Etten-Leur

The Netherlands

www.sysmex.nl

+31 (0)76 508 6000

+31 (0)76 508 6086

info@sysmex.nl

Sysmex Belgium N.V.

Chaussée de Bruxelles 135A

1310 La Hulpe

Belgium

www.sysmex.be

+32 (0)2 769 7474

+32 (0)2 7697499

info@sysmex.be

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