CyFlow™ CD10 Alexa Fluor™ 700

Alternative Name: | CALLA, NEP, gp100 |
Antigen: | CD10 |
Application: | Flow cytometry |
Clonality: | monoclonal |
Clone: | MEM-78 |
Emission Maximum: | 723 nm |
Excitation Maximum: | 702 nm |
Field of Interest: | Immunophenotyping |
Fluorochrome: | Alexa Fluor™ 700 |
Isotype: | IgG1 |
Laser: | Red |
Regulatory Status: | RUO |
Source Species: | Mouse |
Target Species: | Human |
Bestelnummer: | AN915206 |
CyFlow™ CD10 Alexa Fluor™ 700
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HLDA Workshop | HLDA IV—WS Code B 506 HLDA V—WS Code B CD10.4 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | NALM-6 human pre-B cell line |
Background Information | CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100 kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptides. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |